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The effect of ascorbic acid ingestion on the biochemical and physicochemical risk factors associated with calcium oxalate kidney stone formation. Barness, L. Safety considerations with high ascorbic acid dosage. NY Acad. Dresser, G. Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome p 3A4 inhibition.

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Grapefruit warning label: now official in some countries. Drugs Ther.

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Terfenadine: now only available on prescription. Astemizole Hismanal : only available on prescription. Bailey, D. Ethanol enhances the hemodynamic effects of felodipine. Grapefruit juice—felodipine interaction in the elderly. Pharmacokinetic—pharmacodynamic consequences and clinical relevance of cytochrome P 3A4 inhibition.

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    Ranganna, S. The Bible states in the book of Genesis that Adam and Eve had made their own fig leaf clothing: "And the eyes of them both were opened, and they knew that they were naked; and they sewed fig-leaves together, and made themselves girdles".


    Rabbi Nechemia , based on the Talmud, supports the idea that the fruit was a fig , as it was from fig leaves that God made garments for Adam and Eve upon expelling them from the Garden. Since the fig is a long-standing symbol of female sexuality, it enjoyed a run as a favorite understudy to the apple as the forbidden fruit during the Italian Renaissance. The most famous depiction of the fig as the forbidden fruit was painted by Michelangelo Buonarroti in his masterpiece fresco on the Sistine Chapel ceiling. Proponents of the theory that the Garden of Eden was located somewhere in what is now known as the Middle East suggest that the fruit was actually a pomegranate , a plant indigenous from Iran to the Himalayas and cultivated since ancient times.

    Rabbi Yehuda proposes that the fruit was wheat , because "a baby does not know to call its mother and father until it tastes the taste of grain. In Hebrew, wheat is "khitah", which has been considered to be a pun on "khet", meaning "sin".

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    Although commonly confused with a seed, in the study of botany a wheat berry is technically a simple fruit known as a caryopsis , which has the same structure as an apple. Just as an apple is a fleshy fruit that contains seeds, a grain is a dry fruit that absorbs water and contains a seed.

    The confusion comes from the fact that the fruit of a grass happens to have a form similar to some seeds. A fresco in the 13th-century Plaincourault Abbey in France depicts Adam and Eve in the Garden of Eden, flanking a Tree of Knowledge that has the appearance of a gigantic Amanita muscaria , a psychoactive mushroom.

    Allegro proposed the mushroom as the forbidden fruit. The similarities of the story to the story of Pandora's box were identified by early Christians such as Tertullian , Origen , and Gregory of Nazianzus. According to the Quran , Surah Al-A'raf describes Adam and his wife in Paradise where they may eat what is provided, except that they may not eat from one particular tree , lest they be considered Zalimun wrongdoers.

    Then when they tasted of the tree, that which was hidden from them of their shame became manifest to them and they began to cover themselves with the leaves of Paradise. The Quran holds both Adam and his wife accountable for eating the forbidden fruit. As punishment, they were forced to leave the garden, banished from Heaven and sent to the Earth where they were forgiven after repenting.

    The fruit is commonly either identified with wheat or with grapevine in Islamic tradition. From Wikipedia, the free encyclopedia. For other uses, see Forbidden fruit disambiguation. Main articles: Tree of the knowledge of good and evil and Original sin. This section needs additional citations for verification. Please help improve this article by adding citations to reliable sources.